Ilk CLIA Kit for Mouse(Mus musculus) | EIAab.comIlk CLIA Kit for Mouse(Mus musculus)

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Ilk (Gene name),

Integrin-linked protein kinase (Protein name ), ILK_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Ilk;

Protein name:

Integrin-linked protein kinase;

Alternative:

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with cytoplasmic domain of beta 1 subunit of integrin. Could also interacts with beta 2, beta 3 and/or beta 5 subunit of integrin. Interacts (via ANK repeats) with LIMS1 and LIMS2. Interacts with parvins. Interacts (via ANK repeats) with EPHA1 (via SAM domain); stimulated by EFNA1 but independent of the kinase activity of EPHA1 (By similarity). Interacts with TGFB1I1.

Function:

Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.

Subcellular Location:

Cell junction focal adhesion Cell membrane Peripheral membrane protein Cytoplasmic side

Protein Attributes:

Sequence length:

452

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

452:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

O55222

UniGene:

Mm.274846

Pfam:

PF00023

SMR:

O55222

KEGG:

mmu:16202

STRING:

10090.ENSMUSP00000033182

Uniprot:

O55222

FOR

ELISA Kit for Mouse Integrin-linked protein kinase

Cat.:

E1587r

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96T

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ELISA Kit for Mouse Integrin-linked protein kinase

Cat.:

E1587h

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96T

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ELISA Kit for Mouse Integrin-linked protein kinase

Cat.:

E1587m

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96T

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ELISA Kit for Mouse Integrin-linked protein kinase

Cat.:

E1587b

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96T

CLIA Kit for Mouse Integrin-linked protein kinase

Cat.:

U1587b

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MSDS:

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96T

CLIA Kit for Mouse Integrin-linked protein kinase

Cat.:

U1587m

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Integrin-linked protein kinase

Cat.:

U1587h

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Integrin-linked protein kinase

Cat.:

U1587r

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse Integrin-linked protein kinase

Cat.:

P1587Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Integrin-linked protein kinase

Cat.:

P1587Rb-m

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40ug/0.2ml

Polyclonal Antibody for Mouse Integrin-linked protein kinase

Cat.:

P1587Rb-r

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40ug/0.2ml

Polyclonal Antibody for Mouse Integrin-linked protein kinase

Monoclonal Antibody for Mouse Integrin-linked protein kinase

Protein for Mouse Integrin-linked protein kinase

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Identification and characterization of a mouse protein kinase that is highly homologous to human integrin-linked kinase."
Li F. , Liu J. , Mayne R. , Wu C.
Biochim. Biophys. Acta1358:215-220(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: BALB/c.
tissue: Heart.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: FVB/N.
tissue: Mammary tumor.
3.

"Oligomerizing potential of a focal adhesion LIM protein Hic-5 organizing a nuclear-cytoplasmic shuttling complex."
Mori K. , Asakawa M. , Hayashi M. , Imura M. , Ohki T. , Hirao E. , Kim-Kaneyama J.-R. , Nose K. , Shibanuma M.
J. Biol. Chem.281:22048-22061(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TGFB1I1
4.

"Affixin activates Rac1 via betaPIX in C2C12 myoblast."
Matsuda C. , Kameyama K. , Suzuki A. , Mishima W. , Yamaji S. , Okamoto H. , Nishino I. , Hayashi Y.K.
FEBS Lett.582:1189-1196(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
5.

"Kindlin-2 controls bidirectional signaling of integrins."
Montanez E. , Ussar S. , Schifferer M. , Bosl M. , Zent R. , Moser M. , Fassler R.
Genes Dev.22:1325-1330(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH FERMT2
6.

"SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-426;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Embryonic fibroblast.

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